Fluoroquinolones and rifampin combination in the backdrop of heteroresistant tuberculosis.

• Tác giả: Onno W Akkerman, Christopher J Allende, Gunavanthi D Boorgula, David M Engelthaler, Tawanda Gumbo, Sanjay Singh, Shashikant Srivastava, Marieke G G Sturkenboom, Tania A Thomas, Vanessa B Vogensen
• Ngôn ngữ: eng
• Ký hiệu phân loại: 271.6 *Passionists and Redemptorists
• Thông tin xuất bản: United States : Antimicrobial agents and chemotherapy , 2025
• Bộ sưu tập: NCBI
• ID: 60642

Tóm tắt

The impact of heteroresistance on tuberculosis (TB) treatment outcomes is unclear, as is the role of different rifampin and isoniazid exposures on developing resistance mutations. Hollow fiber system model of TB (HFS-TB) units were inoculated with drug-susceptible