Mis-splicing of a neuronal microexon promotes CPEB4 aggregation in ASD.

• Tác giả: Andreea Balaceanu, Anna Bartomeu, Giuseppe Battaglia, Kai Chit Cheung, Cesare De Pace, Berta Duran-Arqué, Marcos Fernández-Alfara, Jesús García, Carla Garcia-Cabau, Rubén Hervás, Kresten Lindorff-Larsen, José J Lucas, Judit Martín, Raúl Méndez, Sara Picó, Julia Pose-Utrilla, Lorena Ruiz-Pérez, Xavier Salvatella, Giulio Tesei
• Ngôn ngữ: eng
• Ký hiệu phân loại: 306.88 Alteration of family arrangements
• Thông tin xuất bản: England : Nature , 2025
• Bộ sưu tập: NCBI
• ID: 607240

Tóm tắt

The inclusion of microexons by alternative splicing occurs frequently in neuronal proteins. The roles of these sequences are largely unknown, and changes in their degree of inclusion are associated with neurodevelopmental disorders