Discovery and configurations assignment of Ile/Leu-containing cyclic peptides with cytotoxic activity, Reniochpeptins A-D, from the marine sponge Reniochalina sp.

• Tác giả: Hou-Wen Lin, Xin-Li Lin, Shu-Ping Wang, Ying Wu, Zong-Mei Wu, Ya-Jun Zeng, Kai-Xuan Zhan, Shuai-Shuai Zhang, Si Zhang, Yuan-Yuan Zhang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 627.9 Other hydraulic structures
• Thông tin xuất bản: England : Phytochemistry , 2025
• Bộ sưu tập: NCBI
• ID: 60995

Tóm tắt

Four previously undescribed cyclic peptides, reniochpeptins A-D (1-4), were isolated from the marine sponge Reniochalina sp. Their structures were elucidated through comprehensive spectroscopic analyses and a modified advanced Marfey's method. This method utilized ultra-high-performance liquid chromatography coupled with tandem multiple reaction monitoring mass spectrometry, employing a CORTECS T