In vivo CRISPR-Cas9 genome editing in mice identifies genetic modifiers of somatic CAG repeat instability in Huntington's disease.

• Tác giả: António Azevedo, Zoe Burch, Jeffrey B Carroll, Kevin Correia, Steven Crescenti, Brigitte Demelo, Cameron Douglas, Emanuela Elezi, Tammy Gillis, James F Gusella, Maheswaran Kesavan, Marina Kovalenko, Marcy E MacDonald, Eduarda Mota-Silva, Ricardo Mouro Pinto, Ryan Murtha, Esaria Oliver, Marion J Riggs, Shota Shibata, Jessica Ulloa, Antonia Vitalo, Vanessa C Wheeler
• Ngôn ngữ: eng
• Ký hiệu phân loại: 621.82 Machine parts
• Thông tin xuất bản: United States : Nature genetics , 2025
• Bộ sưu tập: NCBI
• ID: 61006

Tóm tắt

Huntington's disease, one of more than 50 inherited repeat expansion disorders