Synthesis of a di-O-acylated deoxynojirimycin (DNJ) derivative and evaluation of its antibacterial and antibiofilm activity against Staphylococcus aureus and Stenotrophomonas maltophilia.

• Tác giả: Rosaria Artiano, Daniele D'Alonzo, Eliana De Gregorio, Stefano D'Errico, Anna Esposito, Vincenzo Firpo, Annalisa Guaragna, Antonella Migliaccio, Maria Stabile
• Ngôn ngữ: eng
• Ký hiệu phân loại: 378.242 Thesis and dissertation requirements
• Thông tin xuất bản: Netherlands : Carbohydrate research , 2025
• Bộ sưu tập: NCBI
• ID: 61218

Tóm tắt

Herein we report the synthesis of a novel di-O-acylated DNJ derivative, conceived to study whether iminosugar derivatization with a lipophilic acyl moiety could positively affect its antibacterial properties. The well-known PS-TPP/I