C-terminal amides mark proteins for degradation via SCF-FBXO31.

• Tác giả: Viola Beier, Jeffrey W Bode, Martina Cernakova, Jacob E Corn, Annina Denoth-Lippuner, Jakob Farnung, Lukas T Henneberg, Raphael Hofmann, Sebastian Jessberger, Martin Jinek, Filip Kalčic, Matthias Mann, Matthias F Muhar, Ajse S Nievergelt, Marwa Peters Al-Bayati, Moritz M Pfleiderer, Brenda A Schulman, Nikolaos D Sidiropoulos
• Ngôn ngữ: eng
• Ký hiệu phân loại: 523.887 Terminal stages
• Thông tin xuất bản: England : Nature , 2025
• Bộ sưu tập: NCBI
• ID: 61468

Tóm tắt

During normal cellular homeostasis, unfolded and mislocalized proteins are recognized and removed, preventing the build-up of toxic byproducts