N-Protonated Acridinium Catalyst Enables Anti-Markovnikov Hydration of Unconjugated Tri- and Disubstituted Olefins.

• Tác giả: Tobias Ritter, Boris Alexander van der Worp
• Ngôn ngữ: eng
• Ký hiệu phân loại: 271.6 *Passionists and Redemptorists
• Thông tin xuất bản: United States : Journal of the American Chemical Society , 2025
• Bộ sưu tập: NCBI
• ID: 61584

Tóm tắt

The preparation of alcohols with anti-Markovnikov selectivity directly from olefins and water is a sought-after reaction due to its atom-economy and potential cost-effectiveness. Herein, we present the first general method for direct, catalytic anti-Markovnikov hydration of unconjugated tri- and disubstituted olefins. The key advancement is made possible by an oxidative (