Influence of soil type on bacterial growth and tolerance to experimentally added human antibiotics.

• Tác giả: Manuel Arias-Estévez, Montserrat Díaz-Raviña, David Fernández-Calviño, Elena García-Campos, Laura Rodríguez-González, Vanesa Santás-Miguel, Beatriz Sevilla-Morán, Juan José Villaverde
• Ngôn ngữ: eng
• Thông tin xuất bản: Netherlands : Ecotoxicology and environmental safety , 2025
• Bộ sưu tập: NCBI
• ID: 61674

Tóm tắt

The human antibiotics cefuroxime (CXM) and azithromycin (AZI) are among the most commonly prescribed. A significant portion of both are excreted and has been detected in sewage treatment plant effluents. The increasing use of such effluents in crops for irrigation and as fertilisers poses a threat to soil microbiota because of the presence of antibiotics. The lack of studies on CXM and AZI in soils hinders our understanding of their potential toxic effects on soil bacterial communities and ecosystem services. This study significantly contributes to the literature by quantifying the toxicity of CXM and AZI at varying concentrations in 12 different crop soils and tracking their evolution over time. The study also examined whether antibiotic pressure led to the development of more tolerant bacterial communities. The results of this study are the values of the logarithm of the antibiotic concentration at which 50 % of bacterial growth is inhibited (Log IC