The research focused on establishing main tests for quality control of antivenom production in Vietnam. The results indicated that it's protein concentration, osmolarity and pH were in normal limit, according to WHO Guidelines. The effective dose (ED50) of BC and BM antivenom was 57.14 LD50/ml = 123.9ug/ml. The results were certificated by National Institute for Control of Vaccine and Biologicals, MOH, Vietnam.