Nghiên cứu nồng độ t-pa và pai-1 ở bệnh nhân nhồi máu não giai đoạn cấp

• Tác giả: Tứ Cương Ngô, Đình Toàn Nguyễn, Duy Thăng Nguyễn, Ngọc Quang Nguyễn, Thị Hồng Hạnh Nguyễn, Thị Thùy Loan Phan, Văn Hy Phan, Văn Lượng Trần
• Ngôn ngữ: vie
• Ký hiệu phân loại: 616.81 *Cerebrovascular diseases
• Thông tin xuất bản: Y học Việt Nam, 2011
• Mô tả vật lý: 121-128
• Bộ sưu tập: Metadata
• ID: 622048

Tóm tắt

 Research objective: The aim of this study is to evaluate:- The change of plasma t-PA and PAI-1 in the acute phase of ischemic stroke
  - The correlation between t-PA and PAI-1 and clinical outcome. Research design: - 30 patients with the acute ischemic stroke and 28 control persons at Hue central hospital
  - The plasma t-PA and PAI-1 are measured with the ELISA method
  - The clinical outcome is evaluated with the the score of NIH-NINDS.Result: - Plasma t-PA in the patient group is significatly higher than control group: 8.46 + or - 7.28 ng/ml comparing with 6.66 + or - 3,29 ng/ml (P0.05)
  - Plasma PAI-1 in the patient group is significatly higher than control group : 92.93 + or - 16.5 ng/ml comparing with 44.18 + or - 17.56 ng/ml (P 0.001)
  - There was a strong correlation between clinical outcome and plasma t-PA with r