Background: It is necessary to have an overview of the causes, clinical and endoscopy characteristics. This helps doctors to have the rapid diagnosis and suitable treatment attitudes for cases of gastroduodenal hemorrhage. From these requirements, we studied the situation of gastroduodenal hemorrhage in Hue Central Hospital and Hue University of Medicine and Pharmacy from March, 2009 to April, 2010. Objectives:- Survey some clinical characteristics, common causes and endoscopy image of Gastroduodenal hemorrhage. - Assess the relationship between causes injury image on endoscopy to the level of bleeding. Subjects and methods: Choose patients who were diagnosed gastroduodenal hemorrhage in department of Digestion Internal, Hue Central Hospital and Department of Internal Medicine, Hue University of Medicine and Pharmacy from it March, 2009 to April, 2010. Gastrointestinal endoscopy with soft probe, Olympus GIF-XQ 140 - grading bleeding by Rockall standard. Processing data: Using the program Medcal-Excel 2003. Results: The causes of gastroduodenal hemorrhage were stomach ulcer 27.9 percent, duodenal unlcer 26.7 percent, gastritis 15.1 percent. Clinical: level of bleeding - 48, mild level: 8 percent, average level: 43.1 percent, severe level: 8.1 percent. Endoscopy: the front position of duodenum was 16.27 percent, antrum was 13.95 percent, cardiac stomach- esophagus, the back position of duodenum was 10.47 percent. The cause of stomach ulcer having level of bleeding: severe + average: 43.2 percent, duodenal unlcer having level of bleeding: severe + average: 38.6 percent. Conclusions: The cause of bleeding due to duodenal unlcer and stomach ulcer accounts for high rate. Gastrointestinal bleeding often vomited blood and food bruising, duodenum bleeding often vomited black, diluted blood. Position of the small curvature and the back position of duodenum often bled in severe and average level.