The aim of research: To evaluate the results of primary PCI in acute myocardial infarction at Thanh Hoa General Hospital, from December 2009 to March 2011. Method: Cross-sectional study. Result: 99 patients diagnosed as acuret myocardial nfarction, were treated with primary PCI. 97 patients underwent primary PCI with a procedural success rate of 97.98 percent. In-hospital cardiac mortality after primary PCI was 2.02 percent (01 patient with acute stent thrombosis and 1 patient with complex ventricular arrhythmia), do not get the complications: stroke, vascular accessl problems, contrast nephropathy. Conclusion: The results of primary PCI acute myocardial infarction at Thanh Hoa General Hospital is successful in the fisrt tage, to hope getting better result and decreasing overload phenomenon in the national level of hospitals in the future.