The study was conducted at Hai Phong Children Hospital with the following objectives: Examining the incidence, describing clinical and laboratory properties, and finding some determinants of neonatal urinary tract infection. Population included 1021 newborn infants in which 56 newborn infants were really affected by urinary tract infection. Method: It was prospective and descriptive study. Results: The incidence of neonatal urinary tract infection was 5.48 percent. Non specific clinical courses included: jaundice (71 percent), phimosis in male newborn infants (50 percent), digestive trouble (44 percent), respiratory distress (41 percent), fever, and less frequency of crying at urination. Blood test showed hyperneutrophiles (51 percent) and increased CRP (42 percent). Positive urine culture was 32 percent, gram negative bacteriuria 83 percent. Of which E. coli was 33 percent, Citrobacter 22 percent. Isolated bacteriuria were sensitive to antibiotics such as: Imipeneme, Cefotaxime, Ceftriaxone, Amikacine. Most of bacteria resisted to Ampicilnne, Cotrimoxazole. Determinants factors were premature, pathologic jaundice, asphyxia, phimosis, genito-urinary infection, darken amniosis, early amniotic fracture. Conclusions: The incidence of neonatal urinary tract infection was still high, clinical courses were non specific, and bacteriuria was mainly gram negative.