Manipulation of Surface Potential Distribution Enhances Osteogenesis by Promoting Pro-Angiogenic Macrophage Polarization via Activation of the PI3K-Akt Signaling Pathway.

• Tác giả: Yunyang Bai, Qun Cui, Xuliang Deng, Yaru Guo, Boon Chin Heng, Lulu Liu, Shuo Liu, Yang Liu, Yanhui Lu, Jia Song, Mingming Xu, Fuping You, Xuehui Zhang, Xiaona Zheng
• Ngôn ngữ: eng
• Ký hiệu phân loại: 535.52 Polarization
• Thông tin xuất bản: Germany : Advanced science (Weinheim, Baden-Wurttemberg, Germany) , 2025
• Bộ sưu tập: NCBI
• ID: 622517

Tóm tắt

Regulation of the immune response is key to promoting bone regeneration by electroactive biomaterials. However, how electrical signals at the micro- and nanoscale regulate the immune response and subsequent angiogenesis during bone regeneration remains to be elucidated. Here, the distinctly different surface potential distributions on charged poly(vinylidene fluoridetrifluoroethylene) (P(VDF-TrFE)) matrix surfaces are established by altering the dimensions of ferroelectric nanofillers from 0D BaTiO