Control food safety is a critical requirement to warn of hazards that increase public awareness. Perform tasks sanitary control of food safety annually, the examination of pesticide residues was carried out, heavy metals and microorganisms in vegetable and fruit in market at Northern and Central in the years (2008 - 2010). Analysis results show that the rate of fruit and vegetable samples detected pesticides MRLs from 9.8 to 13.4 percent in (2008-2010). The rate of leaf vegetables sample has highest pesticides MRLs. The results detected 27 pesticides, which 16 pesticides MRLs in vegetable samples analyzed over the years. The active ingredient has a high frequency of appearance in the vegetable are Pyrethroids (Cypermethrin, Permethrin), Organic phosphorus (Chlorpyriphos, Acephate), Carbendazim. Hanoi has sample rate vegetables pesticides MRLs is the highest. Hue is lowest. Analysis results also showed that the sample rate detected nitorat MRLs from 24.5 to 37.0 percent in 2010, higher than in 2009 (from 2.5 to 5.0 percent). The samples rate detected E. coli bacteria MRLs from 73.5 to 100 percent in 2010, higher than 2009 (from 7.5 to 12.5 percent) and the sample rate detected Salmonella from 6.1 to 35.2 percent in 2010, higher than 2009 (from 7.5 to 15.0 percent). Not detect any form of heavy metal MRLs in 2009. Detection rate of 1.33 percent of the samples Pb MRLs in 2010.