Various regions in Vietnam also provide an ideal climate for Phytophthora species to flourish, and the genus Phytophthora is responsible for extensive economic damage in a wide range of different crops, including rubber. Biological control involves the use of the beneficial organisms, their genes, and/or products, such as metabolites, that reduce the negative effects of plant pathogens and promote positive responses by the plant. Antagonist belong to the genus Trichoderma are among the most commonly isolate soil fungi. Due to their ability to protect plants and contain pathogen populations under different soil condition, these fungi have been widely studies and commercially marketed as biopesticides, bio-fertilizers and soil amendments Trichoderma spp. also produce numerous biologically active compounds, including cell wall degrading enzyme, and secondary metabolites. The author focus on the biological, ecological aspects of Trichoderma asperellum in this topic.