Like other developing countries, Vietnam is facing with the increasing trend of road traffic accident. In order to get scientific facts and figures to plan an intervention program and provide a baseline data for evaluation on the effectiveness of the intervention program in Ho Chi Minh city, a descriptive retrospective design was carried out and its result as follows: In 3 years (2005-2007), number of road traffic accident has been increasing by years. Proportion of deaths has also been increasing 3.9 percent in 2006 and 6.8 percent in 2007. In which, Proportion of traffic accident by motorcylces has been increasing, 9.4 percent and 2.3 percent respectively. Proportion of deaths due to motorcylce accident has also been increasing 12.3 percent and 6.3 percent, respectively. Those findings give a alarming sound that road traffic accident is a big problem in HCM city now and emergency measures required.