Presentation of a clinical case of cavernous venous malformation with an unusual location and clinical presentation, detailing its clinical, radiological characteristics, diagnosis, and therapeutic management. The case involves a 37-year-old man with intense headache and incidental diagnosis of infraorbital nerve neurofibroma by imaging tests. After surgical removal and pathological anatomy study, he was finally diagnosed with cavernous venous malformation of the infraorbital canal. Orbital cavernous venous malformation can present unusual manifestations that complicate its diagnosis. The combination of clinical symptoms and imaging tests is usually sufficient for diagnosis, but in cases of unusual clinical presentation, the role of pathological anatomy is essential.