From 25 January 2002 to 11 May 2004, there were 200 patients operated at National Hospital of Endocrinology for treatment of Grave's desease. Ratios of malelfemal was approximately 2/8. Most of them were in range of age from 20 to 49 years old (81.0 percent). The operative indication included the euthyriod cases. The preoperative preparing by Lugol solution, Prednisolon was necessary done. The techniques of operation included: total thyroidectomy for 14 patients (7 percent), near total thyroidectomy with small amount of thyroid tissue left at the superior pole for 9 (4.5 percent), and with posterior wall remnant for 177 (88.5 percent). The total thyroidectomy was performed for patients who were accompanied with nodules, were allergic to synthese antithyroid drugs, or severe ophthalmopathy. There were no mortality as well as thyroid storm and tarchycardy after operation. There were 3 cases reoperated due to hemorrage, 3 cases of trancient hoarsenesse (1.5 percent), 19 cases of trancient hypocalcimea(9.5 percent). Only 64 patients came to hospital for reexamination at 3 months after operation. Among them, there were 58 euthyroid cases (90.7 percent) with FT4 in normal limit.