Twenty seven piglets weaned at 28 days of age (7.12 kg body weight) were selected and divided randomly into 3 groups balanced for sex, weight to evaluate the effect of rice distiller's residue on growth perfonnance, microflora, morphology of small intestine in post weaning pig period. In each group, the piglets were divided randomly into 3 pens (replicates), and each group was fed one of 3 diets for 56 days. A basal diet without rice distille's residue was used as a control diet, and the other 2 groups were fed the control diet with inclusion of rice distiller's residue at 15 percent and 30 percent in dry matter. At 14 days of experiment, 3 piglets from each diet were slaughtered to evaluate the effect of rice distiller's residue on microflora, morphology. Replacement of protein from rice distiller's residue effected on daily feed intake (P0.05) in the priod after weaning to 8 weeks but did not effect on daily weight gained (P 0.05). Using rice distiller's residue was effect on micfoflora in digestive tract of piglets, specially reducing E. eoliin stomach and ileum of piglets. There were significant differences (P0.05) in duodenal villus height and jejunal villus height in piglet fed rice distiller's residue at 15 percent (423 pm, 381 pm) in comparision with control diet (237 pm, 294 pm, respectively). Duodenal villi were wider (P0.05) in the piglets fed rice distiller's residue at 15 percent in dry matter (151 pm) than in the control diet (121 pm). No differences were observed in the duodenum of density of crypt Density crypt increased in ileum among piglets fed rice distiler's residue in comparision with control diet.