Study was conducted on 273 women with recurrent miscarriage and 11 women having multiple failed in-vitro fertilization. The anticardiolipin concentrations were determined by enzyme-linked immunosorbent technique assay (ELISA). The results showed that: In the group of women with recurrent miscarriage, 13.9 percent were positive for anticardiolipin - IgM, 2.9 percent were positive for anticardiolipin - IgG. There was 1/11 woman having in vitro fertilization with positive anticardiolipin - IgG. There were 3 women with recurrent miscarriage positive for both anticardiolipin IgG, IgM. The average concentration of anticardiolipin IgG in womer positive for anticardiolipin - was 22.82 + or - 9.54 U/mL, in women negative was 4.87 + or - 2.37 U/mL. The average concentration of anticardiolipin IgM in women positive for anticardiolipin was 13.47 + or - 5.58 U/mL, in women negative was 4.53 + or - 2.1 U/mL.