The research was conducted to study clinical presentation and outcome of rubella encephalitis at National Hospital for Tropical Diseases. The results show that 48 rubella encephalitis patients were analyzed (22 males, 26 females), age 18.5 + or - 6.5 years, 95.8 percent were not vacinated for rubella. The common symptoms were fever 97.9 percent, rash 95.8 percent, coma 95.8 percent, aggressive 68.8 percent, seizure 60.4 percent. CSF findings: 97.9 percent pandy (+)
leukocytosis mean 77.6 + or - 60.1 cell/mm3, lympho 63.9 + or - 27.9 percent
protein average 0.73 + or - 0.25 g/l. All patients survived, average hospitalized and coma period were 7.7 + or - 4.7 days and 2.8 + or - 1.2 days respectively, no sequelae observed. In conclusions, the common symptoms of rubella encephalitis were fever, rash, coma, aggressive and seizure. All rubella encephalitis patients survived rapidly without sequelae observed.