Reading is a great way leading people to the world of knowledge. One's reading competence, however, may be affected by many factors such as his reading habit, reading interest or types of reading materials used and so on. This descriptive correlational study attempts to analyse some key factors and establish relationship between the profile of students to their reading competence. The study sought to answer the question of whether there are any significant ralationships between the profile of students and their competence in reading English texts. The respondents of the study were 66 English major students of the College of Sciences, Thai Nguyen University in the first semester of the academic year 2010-2011. The findings revealed that there is significant relationship between reading comprehension ability and vocabualry ability, types of reading materials used during lesson, location of high school which graduated from.