Background: Fibromyalgia is a syndrom manifesting clinically in chronic diffuse pain in muscle, ligaments, tendons, connective tissue...on the body with specific tender points and many other symptoms like sleep problem. joint stiffness, fatigue, depression...lt is not well-knowned in Vietnam yet. Purpose: anouncing a ACR-criteria well-matched and successfully treated patient. Subject and method: case report of patient Nguyen Manh L. Conclusion: Fibromyalgia can easily diagnosed according to ACR-criteria and can be successfully treated with recommended anti epileptic drugs in combination with amitriptylin.