Fourniers syndrome is a specific infectious disease in the external genitalia and perineal. This is a surgical emergency, rare but high mortality rates (4-75 percent) due to septic shock and multiple organ failure. Even when it healed it also left many serious sequelea. From 2/2011 to 6/2011, in Wound Healing Unit (National Institute of Burns, Hanoi, Vietnam), the authors have received and successfully treated four patients with necrotizing perineal. region by Fourniers syndrome. Through this research, the authors want to contribute some knowledge about treament of this particular pathology.