Background: Nasopharyngeal carcinoma (NPC) is frequently at Vietnam. In most cases the tumor presents as a painless mass in the upper neck, with possible cervical lymphadenopathy. The most common pattern of tumor diffusion is local infiltration which, given the limitrophe structures, may cause serous otitis, hearing difficulties, nasal obstruction, epistaxis, dysphasia, dysphonia and dysphagia. The purpose the diagnostique clinical, anatomopathological by the stains hematoxylin (HE), the technique immunohistochemistry, arid to comparison with the lesion of tumor primitive. Materials and method: A prospective study from a series 30 patients of NPC, which are 53 cervical lymphadenopathy, is diagnosted clinical and to comparison with the lesion of tumor primitive. Results and discusion: There are 79.2 percent cervical lymphadenopathompy. N3, and 71.7 percent of neck node ayant over 2 cm of the volum. The Kutner neck node is ayant tumor primitive of the lateral and superior walds. There are 4 patiens ayant the metastesis of the cervical lymphadenopathy is not yest the detection the tumor primitive. Conclusion: The cervical lymphadenopathy of the state SIIb is 76.7 percent
and the state III is 23.3 percent.