The author have already studied on NT-proBNP and MPI in 140 spontaneous hypertensive patients with stages of hypertension. MPI is found by Echocardiography. NT-proBNP is measured by analysis patient blood. Average MPI level is 0.52 + or - 0,17 with 95 percent CI: 0.49 - 0.55. Average NT-proBNP level is 45.57 + or - 100.23pg/ml with 95 percent CI: 28.97 - 62.17. MPI has a significant contrary correlation with IVRT, r = -0.26, p0.01, and ET: r