Osteoporosis is a common disease and public health problem, especially in postmenopausal women. Objective: To evaluate the T-score index of heel bone density and leam of factors related to bone density in the women over 50 years old in order to recommend the preventive method to reduce the risk of osteoporosis. Subjects and Methods: The cross-sectional descriptive study was conducted on 222 postmenopause women aged over 50 and 54 healthy women controls at Polyclinic of Vinh Medical University. Results: Mean age was 61.08 + or - 9:38, the number of births was 2.92 + or - 1.32 and starting menopause age was 48.99 + or - 3.78. Prevalence of normal bone density (T-score index or = -1) was 16.2 percent and 83.8 percent for those with reduced bone density and osteoporosis (T-score -1). The older, the more reduced bone density, prevalence of osteoporosis was 70.6 percent among women aged over 70. The longer menopause duration, the more reduced bone density, prevalence of osteoporosis was 52.3 percent among those who had menopause period over 10 years. The lower BMI, the more decreased bone density, especially prevalence of osteoporosis was 54.3 percent for those with BMI less than 18.7. Women with clinical manifestations related to bone and joint disease had lower bone density. Regular exercise reduced the risk of osteoprosis. Condusions and Recommendations: The majority of postmenopausal women with reduced bone density, osteopenia or osteoporosis, dosely related to advanced age, low BMI, longer duration of menopause, bone and joint diseases, regular exercise. Menopausal women should regularly exercise twice a day for at least 30 minutes, measure osteoprosis once a month, regularly control weight and increase physical activity to limit osteoprosis.