The author study 120 patients with lobar pneumonia (LP) in the Respiratory department of National hospital of Pediatrics from August 2012 to the end of July 2013. The most cases are old children, males are more than females. The common clinical symptoms are cough (100 percent) and fever (94.20 percent). 56.70 percent of cases are not heard rales in the both lungs. LP is usually caused by Mycoplasma (36.67 percent), pneumococcus (18.33 percent) and H. Influenza (7.5 percent). 1 case with Influenza A virus. These bacteria are high sensitive with the Quinolone group. Pneumococcal susceptibility with Vancomycin is 100 percent, H. influenza is high sensitive with Azithromycin and Carbapenems.