Nghiên cứu đặc điểm sốt mò và đánh giá hiệu quả điều trị bằng chloramphenicol

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Tác giả: Lê Cẩm Nhung Hồ, Hồng Quang Lê, Huy Hoàng Trần

Ngôn ngữ: vie

Ký hiệu phân loại: 616.92 *Bacterial diseases

Thông tin xuất bản: Tạp chí Y học Việt Nam, 2012

Mô tả vật lý: 84-90

Bộ sưu tập: Metadata

ID: 636627

Aim: To identify epidemiological, clinical, laboratory and treatment of scrub typhus at the Army Hospital 87 from Jan. 2008 to Feb. 2012. Method and results: 174 patients (101 males and 73 females), a median age of 39,51+ or - 12,57, diagnosed with scrub typhus, were enrolled in the prospective and cross-setional stydy. All cases were serologically contimed scrub typhus by using ELISA technique. Most of the cases were dig nosed during the rainy season. Majority of the patients were farmers staying in rural areas and belonged to the age-group of 26-45. The most common clinical features were high fever (100 percent), headache (97,1 percent), eschar (75,9 percent), lymphadenopathy (43,7 percent). vomiting (28,1 percent), diarrhea (20,7 percent), and rash (33,3 percent). Elevated of transaminases were detected in 64,9 percent cases. Blood count showed leucocytosis (10 G/I) in 25,8 percent and thrombocytopenia (100 G/I) in 40,8 percent cases. Common complications were 22,4 percent, among them, 10,9 percent myocarditis. Most of the patients responded well to Chloramphenicol with bout mortality. The average interval to defervescense after treament was 45,65 + or - 26,51hour: The cure rate was 98,3 percent and 1,7 percent relapses. Conclusions: The present of an eschar offers an important clue in making the diagnosis. Chloramphenicol is an effective antibiotic for scrub typhus.
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