The first chemical investigation of Agapetes bracteata (Ericaceae) growing in Lam Dong province, Vietnam led to isolation and structural elucidation of four compound named friedelan-3-one (1), kaempferin (2), myricitrin (3) and quercitrin (4). Their structure were determined by spectroscopic methods including ESI-MS, HR-MS, 1D- and 2D-NMR in comparison with the literature values.