Study objectives: Research and evaluate some prognostic factors of patients with acute ST-elevation myocardial infarction (STEMI) and the relationship between these factors and cardiovascular events. Methods and objects of study: Prospective study describes 45 patients with acute STEMI at Department of Cardiology, Viet-Tiep Hospital - Haiphong (09/2011 - 12/2012), follow for 180 days, record cardiovascular events (death, re-hospitalization for acute coronary syndrome, re-hospitalization due to heart disease, cardiogenic shock, congestive heart failure), survey and evaluate correlation of prognostic factors with cardiac events. Research Results and Conclusions: The rate of cardiac events is 64,4 percent, in which the mortality was 8,8 percent. In patients with a cardiac event within 180 days of follow-up, levels of hsCRP, Troponin I, NTproBNP, score of TIMI and GRACE was significantly higher compared with the group without cardiac events (p 0,05). NTproBNP levels, the TIMI score has a linear correlation pros and left ventricular ejection fraction has an inverse linear correlation with cardiac events.