A new flavonoid, 4"-hydroxycycloartocarpesin (1) besides three known compounds: brosimone-I (2), cycloeucalenol (3) and 2-methyl-D-erythritol 4-O-Beta-D-glucopyranoside (4) were isolated from the wood and stem bark of Artocarpus heterophyllus collected in Hanoi, Vietnam. Their structures were elucidated by analysis of IR, MS, NMR spectra and comparison with the published data. Compounds 3 and 4 have been found for the first time from Artocarpus genus.