Backround and Ojedive: The method of natural orifice transluminal surgery which was developed based on the fundamentals of traditionallaparoscopic surgery, has significantly improved patients' quality of life. The aim of topic is to study the range of applications of single-port laparoscopic surgery, and early results of surgical treatment of gallbladder disease. Methods: A prospective study, cross sectional description, longitudinally follow up. Results: From March 19th, 2010 to November 30th, 2010, eighty-three patients underwent single-port laparoscopic cholecystectomy. The male/female rate was 24/59
the average age was 47.6 + or - 13.5
BMI was 22.3 + or - 2.4 kg/m2 (ranging 18.3-32.9 kg/m2)
the mean operative time was 37.35 + or - 22.73 minutes (there was difference between groups of acute cholecystitis, patients with high risky factors and chronic cholecystitis groups with p 0.05). No difference in incidence rate of complications and postoperative time in the two groups (p 0.05) was found. There was no open conversion and no death. The complication rate was 10.8 percent (including 6 percent of umbilical incision infection, 3.6 percent of bleeding during surgery, and 1.2 percent of abdominal cavity collective fluid). The postoperative stay was 3.73 + or - 0.88 days. Conclusion: Single port laparoscopic cholecystectomy is safe, effective and can be applied to cases of acute cholecystitis and patients with high risky factors such as obesity, previous abdomial surgery and cirrhosis.