Introductions: The laparoscopic approach for appendicectomy in pregnancy was not considered the preferred procedure until recently. The aim of this study was to examine our experience with laparoscopic appendicectomy in pregnancy and review the scientific evidence available in the medical literature. Method: The clinical data of all patients who underwent laparoscopic appendicectomy during pregnancy at Viet Duc hospital between 2009 and 2010 were collected and retrospectively analyzed. A Medline literature search resbicted to English language artides on laparoscopic appendicectomy in pregnancy was carried out. Result: fourty patients underwent appendicectomy during pregnancy. There were 19 laparoscopic appendicectomy . Of these, 5 cases were in the first trimester, 10 cases in the second trimester, and 4 cases in the third trimester. 38 patients had histologically confirmed appendicitis. The mean operating time was 48.24 minutes, and the average postoperative stay in the hospital was 3.12 days. All patients had a full-term normal delivery. Conclusion: The results demonstrate that laparoscopic appendicectomy can be safely performed during all trimesters of pregnancy. The literature search suggests that although laparoscopic appendicectomy in pregnancy is associated with a low rate of intraoperative complications in all trimesters it may be associated with a significantly higher rate of fetal loss compared with open appendicectomy.