BACKGROUND: Sexual health among Chinese men living and working in Guinea has not been adequately studied. AIM: To assess sexual health issues and related factors among Chinese men in Guinea. METHODS: A cross-sectional study was conducted using an anonymous questionnaire, with 258 Chinese male respondents living and working in Guinea. The survey collected data on demographics, lifestyle habits, sexual activity, condom use, and knowledge of sexually transmitted diseases (STDs). OUTCOMES: The primary outcomes included levels of sexual activity, condom use, and STD awareness. RESULTS: Of the respondents, 89.1% reported sexual needs, but only 11.6% were sexually active during their stay. Younger age, urban residence, and non-smoking were positively associated with sexual activity. Among those who were sexually active, 80% had multiple sexual partners, and 60% consistently used condoms, while 13.3% never used them. Condom use was found to be lower among older, married, and less educated individuals. Awareness of STDs was generally low, with an average score of 8.03 out of 12. Younger respondents, those with higher education, those who were sexually active and those who considered themselves familiar with STD knowledge had a relatively higher level of awareness. Most respondents (93%) believed that promoting sexual health education is necessary. CLINICAL IMPLICATIONS: Findings suggest a need for targeted sexual health education and intervention programs, especially among high-risk groups. STRENGTHS & LIMITATIONS: The study provides valuable data on a previously unexamined population
however, its cross-sectional design and reliance on self-reported data may limit the ability to establish causal relationships. CONCLUSION: The study highlights unmet sexual health needs and knowledge gaps among Chinese men in Guinea, suggesting the importance of health education and preventive measures in this population.