Blood and blood component are valuable and nowaday there is not any medicines replates it. Blood transfusion is a effective treatment therapy. Initiactive in seting up plan of blood collection, blood component produce to supply sufficiently and timely is necessary. Objectives: "Study on situation of using blood, blood component in clinical department in NIHBT from 2010 to 2011". Materials: Blood units, blood component units were distributed to patients who were treated in clinical department, NIHBT by Blood group serology department from January 2010 to December 2011. Methods: retrospective study. Results: Total of blood and blood component units which were used in NIHBT from 2010 to 2011 were 159,440 units. Total of blood and blood component units which were used in NIHBT in 2011 increased 1.37 times than 2010. Using of blood and blood component units was the highest on March. Using of blood and blood component units in the quarters in 2011 was much more than the same quarter in 2010. Situation of using blood component: packed red cell (41.9 percent), platelet (27.2 percent), fresh frozen plasma (10.4 percent), frozen plasma (8.4 percent), VIII factor cryoprecipitate (7.2 percent), platelet apheresis (4.9 percent). Using of blood and blood component units was the highest in patients with Leukemia group, and the lowest in patients with bone marrow failure and myelofibrosis group. Conclusions: Need of using blood, blood component increased according to time. Blood and blood component units which were used in NIHBT in 2011 increased 1.37 times than 2010. Using of blood and blood component units was the highest on March. Using of blood and blood component units in the quarters in 2011 was much more than the same quarter in 2010. Using of blood and blood component units was the highest in patients with Leukemia group (35.4 percent).