Cho Ray blood transfusion center collected 211,893 units of blood in three years (2009-2011). Blood was supported by three source including: voluntary donor, paid donor and relative donor. The quantity of blood collection was gradually inreasing to meet the need of using blood in emergency cases, treatment and supporting for some provinces in area. There was an important change from the paid donor source (0.49 percent) to the voluntary donor blood source (97.96 percent). This change was stable and high quality. The whole blood and products used for emergency cases took (10.22 percent) and 76.17 percent for treatment. The rate of whole blood using was low (3.35 percent) while that of products use was high (RBC: 59.20 percent...). By using blood products in treatment will increare safe and economy in blood transfusion.