Autoinhibition of dimeric NINJ1 prevents plasma membrane rupture.

• Tác giả: Kamela Alegre, Phoebe A Chen, Ishan Deshpande, Vishva M Dixit, Shalini Gupta, Matthew C Johnson, Nobuhiko Kayagaki, Kim Newton, Sergei Pourmal, Alexis Rohou, Irma B Stowe, Melissa E Truong, Ying Yang, Yingnan Zhang, Lijuan Zhou
• Ngôn ngữ: eng
• Ký hiệu phân loại: 612.116 Plasma
• Thông tin xuất bản: England : Nature , 2025
• Bộ sưu tập: NCBI
• ID: 641841

Tóm tắt

Lytic cell death culminates in plasma membrane rupture, which releases large intracellular molecules to augment the inflammatory response. Plasma membrane rupture is mediated by the effector membrane protein ninjurin-1 (NINJ1)