The filamins of

• Tác giả: Nicanor González-Morales, Jennifer Johnson, Tiara Mulder
• Ngôn ngữ: eng
• Thông tin xuất bản: Canada : Genome , 2025
• Bộ sưu tập: NCBI
• ID: 642121

Tóm tắt

The actin cytoskeleton is a dynamic mesh of filaments that provide structural support for cells and respond to external deformation forces. Active sensing of these forces is crucial for the function of the actin cytoskeleton, and some actin crosslinkers accomplish it. One such crosslinker is filamin, a highly conserved actin crosslinker dimeric protein with an elastic region capable of responding to mechanical changes in the actin cytoskeleton. Filamins are required across various cells and tissues. In