[WHO classification of melanocytic tumours].

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Tác giả: Maximilian Gassenmaier

Ngôn ngữ: eng

Ký hiệu phân loại: 025.396 *Reclassification

Thông tin xuất bản: Germany : Dermatologie (Heidelberg, Germany) , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 642132

BACKGROUND: The update of the World Health Organisation (WHO) classification of skin tumours has led to new aspects in the classification of melanocytic tumours. OBJECTIVES: Presentation of the classification of melanocytic tumours in light of current clinical, histological and genetic data. MATERIALS AND METHODS: Review of the classification of melanocytic neoplasms in the fifth edition of the WHO classification of skin tumours, taking into account current disease concepts. RESULTS: Malignant melanoma is characterised by stepwise tumour progression and is a heterogeneous disease. Benign and intermediate precursor lesions with characteristic driver mutations can be defined for the different melanoma subtypes. Melanocytomas represent a growing group of intermediate neoplasms which, from a genetic point of view, lie between nevi and melanomas and usually have a benign course. CONCLUSION: With the update of the WHO classification, genetic parameters are becoming increasingly relevant and shape the terminology. New terms such as 'melanocytoma' require a medical understanding of current disease concepts and good physician-patient communication for appropriate reporting of findings and therapy.
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