Elective thoracoscopic surgery for congenital lung malformations: what age to operate?

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Tác giả: Yuzuo Bai, Huimin Jia, Dan Liu, Zhiyi Niu, Yanan Wang, Yuqing Zhao

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: Germany : European journal of pediatrics , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 642225

 PURPOSE: This study aimed to evaluate the characteristics of congenital lung malformations (CLMs) in patients from infancy to adulthood, and to determine the optimal timing for thoracoscopic surgery. METHODS: All patients with CLMs who underwent thoracoscopic surgery between 2017 and 2023 were retrospectively reviewed. The patients were divided into five age groups: 1-6 months, 6-12 months, 1-4 years, 4-16 years, and >
 16 years. Clinical characteristics and surgical outcomes were compared and analyzed for variance among the age groups. RESULTS: A total of 173 patients with CLM were included. Thirteen (7.5%) patients were categorized in the 1-6 months age group, 44 (25.4%) in the 6-12 months age group, 58 (33.5%) in the 1-4 years age group, 30 (17.3%) in the 4-16 years age group, and 28 (16.2%) in the >
  16 years age group. The median age at surgery was 2.3 years (range: 1 month to 74 years). The operative time was shortest in the 1-4 years age group at 86.5 min (interquartile range: 57.3-131.5 min, p <
  0.01). The results of the multivariate regression analysis indicated that age >
  4 years (odds ratio [OR]: 8.70, p <
  0.01) and previous infection (OR: 3.75, p <
  0.01) increased the risk of operative adhesions, which increased the risk of major complications and conversion to open thoracotomy. CONCLUSION: Thoracoscopic surgery for CLMs is safe and feasible at all ages. Age <
  4 years may predict uneventful surgical outcomes due to fewer operative adhesions.
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