In recent decades, freshwater bodies have experienced significant stress due to the excessive disposal of dyes from textile industries and waste antibiotic discharges from pharmaceutical industries. The continuous disposal of these substances may harm the natural ecosystem and generate antibiotic resistance in living organisms. Conventional treatment facilities are inadequate in treating these contaminants effectively, leading to a focused interest in advanced technologies, such as electrooxidation. This study aimed to assess graphite sheet electrode's efficacy in removing methylene blue (MB) dye and antibiotic ciprofloxacin (CIP) under different operating conditions, such as voltage (2.5, 5, and 7.5 V), initial concentration (5, 10, 25, and 50 ppm), pH (3, 6, and 9), and electrolyte (Na