Non-Repeat Segment 1 in Vibrio vulnificus MARTX toxin, which binds to biantennary N-glycans, is essential for host cell blebbing but dispensable for effector translocation.

• Tác giả: Byoung Sik Kim, Yunjeong Kim, Jieun Lee
• Ngôn ngữ: eng
• Ký hiệu phân loại: 808.0428 Rhetoric and collections of literary texts from more than two literatures
• Thông tin xuất bản: Germany : Microbiological research , 2025
• Bộ sưu tập: NCBI
• ID: 643309

Tóm tắt

We read with interest the article by Dr. Satchell and her colleagues, published on bioRxiv, titled "Biantennary N-glycans as Receptors for MARTX Toxins in Vibrio Pathogenesis" (Chen et al., 2024). In that article, the authors utilize AlphFold2 to predict the structure of the repeat-containing regions of the pore-forming multifunctional autoprocessing repeats-in-toxin (MARTX