Acetyl-l-carnitine (ALC) is synthesized in the brain, liver, and kidneys and plays crucial roles in energy metabolism, acetylcholine production, protein synthesis, and neuronal protection, contributing to its antidepressant and neuroprotective properties. Zinc, a vital biometal, is essential for depression and neuroprotection, exhibiting antidepressive effects alone or combined with classical antidepressants. The pharmacological benefits of metal coordination complexes often result from synergistic or additive effects. In this study, we present a novel multifunctional zinc complex, Zn(ALC)Cl