Inflammasome mediated in situ cancer vaccine activated by schottky heterojunction for augmented immunotherapy.

• Tác giả: Qingbin He, Houyang Hu, Yue Hua, Jianwei Jiao, Chengzhilin Li, Zhonghou Rong, Vadim V Shmanaid, Cong Song, Ming Xia, Ziang Xu, Haiyuan Zhang, Nianlei Zhang, Yachao Zhang, Miaoqing Zhao, Runxiao Zheng
• Ngôn ngữ: eng
• Ký hiệu phân loại: 622.22 In-situ processing
• Thông tin xuất bản: Netherlands : Journal of controlled release : official journal of the Controlled Release Society , 2025
• Bộ sưu tập: NCBI
• ID: 644006

Tóm tắt

In situ cancer vaccines have emerged as an attractive paradigm for cancer immunotherapy. Nevertheless, insufficient antigens production, weak antigen presentation and immunosuppressive tumor microenvironment impeded the effectiveness of tumor immunotherapy. Herein, we constructed the NLRP3 inflammasome mediated in situ cancer vaccine (FPLB), in which rod shaped α-Fe