INTRODUCTION: Factors influencing plasma Alzheimer's disease (AD) biomarkers remain incompletely understood. Here we evaluated Fujirebio plasma p-Tau METHODS: Non-Hispanic White (NHW, n = 113), Black/African American (B/AA, n = 66), and Chinese American (ChA, n = 38) participants recruited from two universities were included. We examined if plasma p-Tau RESULTS: CSF p-Tau DISCUSSION: Severity of cognitive impairment and race both influence plasma p-Tau HIGHLIGHTS: Cognitive impairment associates with plasma p-Tau