Two distinct types of systemic amyloidosis-transthyretin (ATTR) and light chain (AL)-account for the majority of cardiac amyloidosis (CA), which have been considered mutually exclusive. Diagnostic confusion can arise when both proteins are identified from an amyloid deposit. We present a rare occurrence of histopathologically confirmed concomitant ATTR and AL CA captured on 99mTc-3,3-diphosphono-1,2-propanodicarboxylic acid (DPD) scan and 18F-flutemetamol (FMM) PET/CT.