Three-Component Sulfonylation and Heteroannulation Enabled by 3-Fold Defluorofunctionalization of Trifluoromethyl Enones.

• Tác giả: Xue-Qiang Chu, Shu-Ji Gao, Danhua Ge, Xue-Ying Huang, Xiao-Ying Li, Mengtao Ma, Zhi-Liang Shen
• Ngôn ngữ: eng
• Ký hiệu phân loại: 006.693 Three-dimensional graphics
• Thông tin xuất bản: United States : The Journal of organic chemistry , 2025
• Bộ sưu tập: NCBI
• ID: 648016

Tóm tắt

Trifluoromethyl enone emerges as a versatile and multifaceted building block in organic synthesis. A defluorinative heterocyclization reaction of readily available β,β-ditrifluoromethylated enones and biocompatible sodium sulfinates has been developed for the modular synthesis of densely functionalized furans with regio-defined