GLP-1RA and SGLT2i utilization in people with type 2 diabetes with atherosclerotic cardiovascular disease (ASCVD) or at high risk of ASCVD in the Gulf Region: Results from the PACT-MEA studys.

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Tác giả: Doaa K Abdalla, Jehan A Abdulla, Hessa M Al Kandari, Usama A AlAlami, Naji M Alamuddin, Waleed A Al-Dahi, Hanan Y Alfadehla, Dalal A AlRomaihi, Shashikanth J Chetty, Amin A Jayyousi, Saeed H Khalaf, Mashhood A Siddique, Guruprasad C Subbarao

Ngôn ngữ: eng

Ký hiệu phân loại: 133.59 Types or schools of astrology originating in or associated with a national group; originating in or associated with a specific religion

Thông tin xuất bản: Saudi Arabia : Saudi medical journal , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 64999

OBJECTIVES: To provide insights into the real-world usage of glucagon-like peptide-1 receptor agonists (GLP-1RAs) and sodium-glucose cotransporter 2 inhibitors (SGLT2i) among individuals with type 2 diabetes (T2D) from Bahrain, Kuwait, and Qatar who either had established atherosclerotic cardiovascular disease (eASCVD) or were at high risk of developing ASCVD. METHODS: This study of 1062 adults diagnosed with T2D from Bahrain, Kuwait, and Qatar is a sub-analysis within the Prevalence and Clinical Management of Atherosclerotic Cardiovascular Diseases in Patients with Type 2 Diabetes across Countries in the Middle East and Africa (PACT-MEA) study, a noninterventional, cross-sectional study. Participants were recruited from 13 primary or secondary care facilities between March and August 2022. Medical records of participants were reviewed to extract relevant data, including demographic characteristics, eASCVD status, ASCVD risk and glucose-lowering treatment. Appropriate descriptive and inferential statistical tests were performed. RESULTS: Among T2D participants with eASCVD, a significantly higher proportion (41.3%) received SGLT2i compared to GLP-1RA (10.5%, CONCLUSION: Despite these cardioprotective agents being recommended by guidelines, the study findings suggest a suboptimal use of GLP-1RA and SGLT2i in a real-world setting.
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